Type 1 Diabetes
Fortunately, most problems involving the skin are benign and not serious. However, hives, as well as various other skin conditions, can indicate that a person has type 1 diabetes.
Diabetes signs and symptoms to look out for on the skin include the development of blisters, persistent fungal infections that occur repeatedly, eruptive xanthomatosis, and dermopathy.
Hives can occur with lupus in some men and women. It affects about 10 percent of people with the disease. Normally, though, a butterfly-shaped rash will appear on the nose and cheeks.
The butterfly rash (called a malar rash) that sometimes occurs with lupus can appear on the face at random or after exposure to sunlight. Often, it appears just before a flare-up.